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Gene Information
Gene symbol: PTHLH
Gene name: parathyroid hormone-like hormone
HGNC ID: 9607
Synonyms: PTHRP, HHM, PLP, PTHR
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCND2 | 1 hits |
| 2 | CDK2 | 1 hits |
| 3 | CDKN2A | 1 hits |
| 4 | FGF2 | 1 hits |
| 5 | HGF | 1 hits |
| 6 | NUDT6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11181569 | Consistent with the in vivo observations, FGF2 inhibited bone growth in culture and induced downregulation of IHH and PTHrP receptor gene expression. |
| 2 | 17686945 | Furthermore, adenovirus-mediated delivery of kinase-dead PKC zeta completely inhibited beta-cell proliferation in primary islet cells overexpressing PTHrP and/or HGF. |
| 3 | 20876711 | Furthermore, the amino terminus PTHrP(1-36) peptide is sufficient to increase replication as well as expression of the late G1/S cell-cycle proteins cyclin E and cyclin-dependent kinase 2 (cdk2) in human islets. |
| 4 | 21800111 | Analysis of islet G1/S cell cycle proteins revealed that chronic overabundance of PTHrP(1-139) in the beta cell significantly increased the cell cycle activator cyclin D2 and decreased levels of cyclin-dependent kinase 4 inhibitor (p16( Ink4a ) [Ink4a also known as Cdkn2a]), but acute treatment with PTHrP(1-36) did not. |