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Gene Information
Gene symbol: PTTG1
Gene name: pituitary tumor-transforming 1
HGNC ID: 9690
Synonyms: PTTG, HPTTG, EAP1, securin
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | NTSR1 | 1 hits |
| 3 | PSIP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17065388 | These results show that mPTTG exhibits properties consistent with a murine securin in insulin-secreting mouse cells and mPTTG overexpression inhibits cell proliferation, suggesting that defective beta-cell proliferation observed in PTTG-/- mice is likely due to abnormal cell-cycle progression. |
| 2 | 18566344 | In fact, p75(NTR) depresses the VEGF-A/Akt/eNOS/NO pathway and additionally reduces the mRNA levels of ITGB1 [beta (1) integrin], BIRC5 (survivin), PTTG1 (securin) and VEZF1. |