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Gene Information
Gene symbol: RAB3A
Gene name: RAB3A, member RAS oncogene family
HGNC ID: 9777
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CREM | 1 hits |
| 2 | INS | 1 hits |
| 3 | PRKAR2A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12510060 | Thus, Rab3A plays an important in vivo role facilitating the efficiency of insulin exocytosis, most likely at the level of replenishing the ready releasable pool of beta-granules. |
| 2 | 16498408 | ICER overexpression diminished the level of Granuphilin, Noc2, Rab3a and Rab27a by binding to cAMP responsive elements located in the promoters of these genes and inhibited exocytosis of beta-cells in response to secretagogues. |
| 3 | 17639022 | Glucagon-like peptide-1 (GLP-1) rescues insulin secretory deficiency in type 2 diabetes partly via cAMP actions on exchange protein directly activated by cAMP (Epac2) and protein kinase A (PKA)-activated Rab3A-interacting molecule 2 (Rim2). |
| 4 | 20807725 | The regulation of insulin exocytosis in rodent ?-cells and responsiveness to incretins are reliant on Rab family members, notably Rab3a and Rab27a, but not Rab3b. |
| 5 | 21099278 | Cast (RIP) islets had modestly reduced expression of Rab3a and other critical components in the late steps of insulin exocytosis. |