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Gene Information
Gene symbol: RALBP1
Gene name: ralA binding protein 1
HGNC ID: 9841
Synonyms: RLIP76, RIP1, RIP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CREB1 | 1 hits |
| 2 | GCG | 1 hits |
| 3 | INS | 1 hits |
| 4 | PRKAA2 | 1 hits |
| 5 | PRKAR2A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20007934 | RLIP76 was induced by oxidative or hyperglycemic stress; the concomitant increase in insulin endocytosis was completely abrogated by inhibiting the transport activity of RLIP76. |
| 2 | 20007934 | Because RLIP76 is induced by oxidative stress, it could play a role in insulin resistance seen in pathological conditions characterized by increased oxidative stress. |
| 3 | 10909973 | Glucagon-like peptide 1 (GLP-1), a hormonal activator of adenyl cyclase, stimulates insulin gene transcription, an effect mediated by the cAMP response element (CRE) of the rat insulin I gene promoter (RIP1). |
| 4 | 10909973 | Here we demonstrate that the signaling mechanism underlying stimulatory effects of GLP-1 on insulin gene transcription results from protein kinase A (PKA)-independent activation of the RIP1 CRE. |
| 5 | 10909973 | Although GLP-1 stimulates cAMP production in rat INS-1 insulinoma cells, we find accompanying activation of a -410-bp RIP1 luciferase construct (-410RIP1-LUC) to exist independently of this second messenger. |
| 6 | 10909973 | On the basis of these studies, it is proposed that PKA-independent stimulatory actions of GLP-1 at RIP1 are mediated by bZIP transcription factors related in structure but not identical to CREB. |
| 7 | 21931813 | The decrease in RLIP76 protein expression by rosiglitazone and metformin is associated with an up-regulation of PPAR? and AMPK. |