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Gene Information
Gene symbol: RAP1A
Gene name: RAP1A, member of RAS oncogene family
HGNC ID: 9855
Synonyms: KREV-1, SMGP21
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | RAPGEF3 | 1 hits |
| 3 | RPS6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20339002 | Although the Epac proteins were originally identified as cAMP-responsive activators of Rap1 GTPases, the role of Rap1 in beta-cell biology has not yet been defined. |
| 2 | 20339002 | Using the Ins-1 rat insulinoma line, we demonstrate that activated Rap1A, but not related monomeric G proteins, promotes ribosomal protein S6 phosphorylation. |
| 3 | 20339002 | Activated Rap1A promotes glucose-stimulated insulin secretion, islet cell hypertrophy, and islet cell proliferation, the latter exclusively through mammalian target of rapamycin complex 1, suggesting that Rap1 is an important regulator of beta-cell function. |