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Gene Information
Gene symbol: RASGRF1
Gene name: Ras protein-specific guanine nucleotide-releasing factor 1
HGNC ID: 9875
Synonyms: CDC25L, CDC25, GRF55, H-GRF55, GNRP, PP13187
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | FOXO3 | 1 hits |
| 2 | GCG | 1 hits |
| 3 | INS | 1 hits |
| 4 | MAPK1 | 1 hits |
| 5 | MMP9 | 1 hits |
| 6 | RAB10 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 3056401 | Insulin treatment (2 h) restored guanine nucleotide exchange factor activity to control values in both muscles. |
| 2 | 3056401 | Also, insulin treatment did not increase guanine nucleotide exchange factor activity in extracts from soleus and heart. |
| 3 | 17389601 | Ectopic expression of Ras-GRF1 was accompanied by ERK activation and elevated levels of MMP-9 in M2A7 cells, whereas a catalytically inactive dominant negative Ras-GRF1, which prevented ERK activation, reduced MMP-9 expression in M2 cells. |
| 4 | 21454697 | This process is expected to require the participation of a guanine nucleotide exchange factor (GEF) to generate the GTP-bound form of Rab10, but this GEF has not hitherto been identified. |
| 5 | 21893988 | The guanine nucleotide exchange factor ?Pix and the adaptor protein p66(Shc) are important players in Akt-independent inactivation of FOXO3a transcription factor. |
| 6 | 21734192 | The model reconstructed satisfactorily the dynamic changes in [cAMP] and predicted the activities of cAMP effectors, protein kinase A (PKA), and cAMP-regulated guanine nucleotide exchange factor [cAMP-GEF or exchange protein directly activated by cAMP (Epac)] during GLP-1 stimulation. |