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Gene Information
Gene symbol: S100A8
Gene name: S100 calcium binding protein A8
HGNC ID: 10498
Synonyms: P8, MRP8, 60B8AG, CGLA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL6 | 1 hits |
| 2 | SERPINE1 | 1 hits |
| 3 | SMAD3 | 1 hits |
| 4 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15198928 | Smad proteins transduce the TGF-beta-mediated signal, and Smad-binding CAGA sequences are present in the plasminogen activator inhibitor-1 (PAI-1) promoter. |
| 2 | 15198928 | Transfection of phosphorothioate CAGA oligonucleotide, a CAGA antisense analog, inhibited Gly-BSA-induced PAI-1 mRNA expression. |
| 3 | 15198928 | These results indicate that Gly-BSA increases DNA binding activity of Smad3 and that it stimulates PAI-1 transcription through Smad-binding CAGA sequences in the PAI-1 promoter in HMC. |
| 4 | 21472666 | Pretreatment of THP-1 with AGE followed by stimulation with IL-6 (10?ng/ml) or TNF? (10?ng/ml) further increased S100A8 and S100A9?mRNA expression and S100A8/A9 release into cell culture supernatant, as compared to pretreatment with non-glycated albumin as control. |