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Gene Information
Gene symbol: S100B
Gene name: S100 calcium binding protein B
HGNC ID: 10500
Synonyms: S100beta
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HNRNPK | 1 hits |
| 2 | NCF1 | 1 hits |
| 3 | PTGS2 | 1 hits |
| 4 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15127201 | In contrast, the reported RAGE ligand S100b was confirmed to induce VCAM-1 expression on endothelial cells and TNF-alpha secretion by PBMCs after 24 h of treatment. |
| 2 | 18854308 | We examined the molecular mechanisms by which the RAGE ligand, S100b, induces COX-2 in monocytes. |
| 3 | 18854308 | S100b significantly increased COX-2 mRNA accumulation in THP-1 monocytes at 2 h via mRNA stability. |
| 4 | 18854308 | Chromatin immunoprecipitation and RNA immunoprecipitation revealed that S100b decreased occupancy of the DNA/RNA-binding protein, heterogeneous nuclear ribonuclear protein K (hnRNPK), at the COX-2 promoter but simultaneously increased its binding to the COX-2 3'-UTR. |
| 5 | 18854308 | S100b treatment promoted the translocation of nuclear hnRNPK to cytoplasm, whereas a cytoplasmic translocation-deficient hnRNPK mutant inhibited S100b-induced COX-2 mRNA stability. |
| 6 | 18854308 | Furthermore, S100b significantly down-regulated the expression of a key microRNA, miR-16, which can destabilize COX-2 mRNA by binding to its 3'-UTR. |
| 7 | 20578796 | SM produced a significant decrease in monocytic interleukin-1? and COX-2 levels and prevented oxidant formation caused by S100b, which appeared to be mediated by inhibition of p47phox membrane translocation. |