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Gene Information

Gene symbol: SERPINE2

Gene name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

HGNC ID: 8951

Synonyms: PN1, GDN, PNI, nexin

Related Genes

#	Gene Symbol	Number of hits
1	C20orf181	1 hits
2	INS	1 hits
3	PLAT	1 hits
4	SERPINE1	1 hits

Related Sentences

#	PMID	Sentence
1	8692017	They aimed to examine the effect of proinsulin and insulin on fasting secretion of plasminogen activator inhibitor type 1 (PAI-1) and tissue plasminogen activator (t-PA).
2	15953128	To explore the role of tissue plasminogen activator (tPA) activity and plasminogen activator inhibitor type 1 (PAI-1) in survivors of a first myocardial infarction (MI).
3	16078580	The following examinations were performed at baseline and after treatment: (1) high-resolution ultrasonography to measure the diameter changes of brachial artery in response to reactive hyperemia (endothelium-dependent) and on administration of glyceryl trinitrate (endothelium-independent); (2) high resolution ultrasonography to measure combined intima-media thickness (IMT) of common carotid arteries (CCA); (3) fasting plasma plasminogen activator inhibitor type 1 (PAI-1) activity, C reactive protein (CRP) and malonic aldehyde(MDA) concentration.
4	16634839	Plasminogen activator inhibitor type 1 is elevated in p-GDM women with IIS and depends on plasma proinsulin and abdominal obesity.
5	17433639	"In vitro" studies have demonstrated that CRP induces plasminogen activator inhibitor type 1 (PAI-1) expression, suggesting a hypofibrinolytic role for CRP.