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Gene Information
Gene symbol: SFRP1
Gene name: secreted frizzled-related protein 1
HGNC ID: 10776
Synonyms: SARP2, FRP, FRP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DACT1 | 1 hits |
| 2 | STAR | 1 hits |
| 3 | WNT2 | 1 hits |
| 4 | WNT5A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19073771 | However, Dact1 knockdown impairs adipogenesis through activation of the Wnt/beta-catenin signaling pathway, and this is reversed by treatment with the secreted Wnt antagonist, secreted Frizzled-related protein 1 (Sfrp1). |
| 2 | 21344486 | While WNT5A, FZD5, and DKK1 were highly expressed in PC3 cells, WNT1 and SFRP1 mRNA levels were higher in DU145 cells. |
| 3 | 15507471 | Accordingly, invasion induced by Wnt-2 was prevented by soluble FRP-3 and FRP-1, sequestration of Gbetagamma subunits, depletion of the GSK-3beta protein by RNA interference, the c-Jun dominant negative mutant TAM67 and was not reversed by wt-Axin. |
| 4 | 21915818 | Wnt antagonist sFRP-1 inhibited adipokine-mediated StAR activity, but did not affect ERK1/2 MAPK activation. |