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Gene Information

Gene symbol: SIRPA

Gene name: signal-regulatory protein alpha

HGNC ID: 9662

Synonyms: SHPS1, SIRP, MYD-1, BIT, P84, SHPS-1, SIRPalpha, CD172a, SIRPalpha2, MFR, SIRP-ALPHA-1

Related Genes

# Gene Symbol Number of hits
1 CD47 1 hits
2 IGF1 1 hits
3 SHC1 1 hits

Related Sentences

# PMID Sentence
1 17652764 For Shc to be phosphorylated, it must be recruited to the cytoplasmic domain of the transmembrane protein SHPS-1 (SHP substrate-1).
2 17652764 This, in turn, was attributable to an increase in SHPS-1 association with integrin-associated protein (IAP), which is necessary for SHPS-1 phosphorylation.
3 17652764 This study demonstrates that hyperglycemic conditions enhance the response of RECs to IGF-I by increasing the association of IAP with SHPS-1 permitting the formation of the SHPS-1-Shc signaling complex, which is required for the proliferative response to IGF-I.