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Gene Information
Gene symbol: SIRPA
Gene name: signal-regulatory protein alpha
HGNC ID: 9662
Synonyms: SHPS1, SIRP, MYD-1, BIT, P84, SHPS-1, SIRPalpha, CD172a, SIRPalpha2, MFR, SIRP-ALPHA-1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
17652764
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For Shc to be phosphorylated, it must be recruited to the cytoplasmic domain of the transmembrane protein SHPS-1 (SHP substrate-1).
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2 |
17652764
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This, in turn, was attributable to an increase in SHPS-1 association with integrin-associated protein (IAP), which is necessary for SHPS-1 phosphorylation.
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3 |
17652764
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This study demonstrates that hyperglycemic conditions enhance the response of RECs to IGF-I by increasing the association of IAP with SHPS-1 permitting the formation of the SHPS-1-Shc signaling complex, which is required for the proliferative response to IGF-I.
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