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Gene Information
Gene symbol: SIRT2
Gene name: sirtuin 2
HGNC ID: 10886
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APC | 1 hits |
| 2 | AURKA | 1 hits |
| 3 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18005249 | In mammals, the Sir2 ortholog Sirt1 promotes fat mobilization, fatty acid oxidation, glucose production, and insulin secretion in response to nutrient availability. |
| 2 | 22014574 | We demonstrated that SIRT2 regulates the anaphase-promoting complex/cyclosome activity through deacetylation of its coactivators, APC(CDH1) and CDC20. |
| 3 | 22014574 | SIRT2 deficiency caused increased levels of mitotic regulators, including Aurora-A and -B that direct centrosome amplification, aneuploidy, and mitotic cell death. |