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Gene Information
Gene symbol: SLC7A1
Gene name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
HGNC ID: 11057
Synonyms: CAT-1, HCAT1, REC1L
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MIRN122 | 1 hits |
| 2 | NR0B2 | 1 hits |
| 3 | NR1H4 | 1 hits |
| 4 | SLC29A1 | 1 hits |
| 5 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15272035 | Gestational diabetes increased hCAT-1 mRNA expression (2.4-fold) and activity, eNOS mRNA (2.3-fold), protein level (2.1-fold), and phosphorylation (3.8-fold), but reduced hENT1 mRNA expression (32%) and activity. |
| 2 | 17427197 | TGF-beta1 and high D-glucose increased hCAT-1 mRNA expression ( approximately 8-fold) and maximal transport velocity (V(max)), L-[(3)H]citrulline formation from L-[(3)H]arginine (index of NO synthesis) and endothelial NO synthase (eNOS) protein abundance, but did not alter eNOS phosphorylation. |
| 3 | 19067360 | It is therefore possible that binding of miR-122 to the 3'UTR may cause the depression of gene expression, contributing to the lesser level of SLC7A1 and the endothelial dysfunction seen in hypertensive subjects. |
| 4 | 21493670 | Mechanistic studies to explain these differences revealed that FXR physically interacts with ERR and protects them from repression by the atypical corepressor, small heterodimer partner in liver. |