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Gene Information
Gene symbol: SLC9A3
Gene name: solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
HGNC ID: 11073
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EGF | 1 hits |
| 2 | EGFR | 1 hits |
| 3 | INS | 1 hits |
| 4 | SGK1 | 1 hits |
| 5 | SLC5A2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21140140 | Conversely, the chronic effect of high glucose (25 mM) increased the pH(i) recovery rate (~40%, P < 0.05), without changes in the total levels of NHE1, NHE3, or SGLT1 expression, but increasing the total cellular (~50%, P < 0.05) and the plasma membrane (~100%, P < 0.01) content of SGLT2. |
| 2 | 18417539 | A lower dose of fatty acids that leads to intracellular lipid accumulation but does not change baseline NHE3 is sufficient to abolish the stimulation of NHE3 by insulin and to partially block the stimulation of NHE3 by glucocorticoid hormones; acid regulation of NHE3 in lipid-loaded OKP cells is not affected. |
| 3 | 16105029 | As the epidermal growth factor (EGF) receptor is activated by both EGF and other factors implicated in diabetic nephropathy, the relationship of SGK-1 with EGFR activity was assessed. mRNA and protein expression of SGK-1 and mRNA expression of the sodium hydrogen exchanger NHE3 were measured in human PTCs exposed to 5 mmol/L (control) and 25 mmol/L (high) glucose. |
| 4 | 16105029 | SGK-1 overexpression increased PTC growth (P < 0.0001), progression through the cell cycle (P < 0.001), and increased NHE3 mRNA (P < 0.01), which were all reversed with PKI166. |