|
Gene Information
Gene symbol: SMURF1
Gene name: SMAD specific E3 ubiquitin protein ligase 1
HGNC ID: 16807
Synonyms: KIAA1625
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
21454619
|
The HECT-type ubiquitin ligase (E3) Smad ubiquitination regulatory factor 1 (Smurf1) targets various substrates, including Smad1/5, RhoA, Prickle 1, MEKK2, and JunB for degradation and thereby regulates adult bone formation and embryonic development.
|
2 |
21454619
|
We show that Smurf1 interacts with WFS1 at the ER and promotes the ubiquitination and proteasomal degradation of WFS1.
|
|