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Gene Information

Gene symbol: SMURF1

Gene name: SMAD specific E3 ubiquitin protein ligase 1

HGNC ID: 16807

Synonyms: KIAA1625

Related Genes

# Gene Symbol Number of hits
1 JUNB 1 hits
2 MAP3K2 1 hits
3 PRICKLE1 1 hits
4 RHOA 1 hits
5 WFS1 1 hits

Related Sentences

# PMID Sentence
1 21454619 The HECT-type ubiquitin ligase (E3) Smad ubiquitination regulatory factor 1 (Smurf1) targets various substrates, including Smad1/5, RhoA, Prickle 1, MEKK2, and JunB for degradation and thereby regulates adult bone formation and embryonic development.
2 21454619 We show that Smurf1 interacts with WFS1 at the ER and promotes the ubiquitination and proteasomal degradation of WFS1.