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Gene Information

Gene symbol: SNAP23

Gene name: synaptosomal-associated protein, 23kDa

HGNC ID: 11131

Synonyms: SNAP23A, SNAP23B, HsT17016

Related Genes

# Gene Symbol Number of hits
1 INS 1 hits
2 SLC2A1 1 hits
3 SLC2A4 1 hits
4 STXBP3 1 hits
5 VAMP2 1 hits
6 VTI1B 1 hits

Related Sentences

# PMID Sentence
1 17922004 We also show that oleic acid treatment decreases the insulin sensitivity of heart muscle cells, and this sensitivity is completely restored by transfection with SNAP23.
2 17922004 Thus, SNAP23 might be a link between insulin sensitivity and the inflow of fatty acids to the cell.
3 20006577 Our results indicate that the t-SNAREs syntaxin4 and SNAP23 are indispensable for the tethering of GLUT4 vesicles to the plasma membrane, whereas the v-SNARE VAMP2 is not required for this step but is essential for the subsequent fusion event.
4 20460426 Our previous studies suggest that the SNARE protein synaptosomal-associated protein of 23 kDa (SNAP23) is involved in the link between increased lipid levels and insulin resistance in cardiomyocytes.
5 20460426 The objective was to determine whether SNAP23 may also be involved in the known association between lipid accumulation in skeletal muscle and insulin resistance/type 2 diabetes in humans, as well as to identify a potential regulator of SNAP23.
6 20460426 Studies in L6 cells showed that Munc18c promoted the expression of SNAP23.
7 20460426 We also showed that Munc18c is a potential regulator of SNAP23.
8 21596547 SNAP23 is involved in the insulin dependent translocation of GLUT4 to the plasma membrane, and has an important role in the development of insulin resistance.
9 21596547 Thus fatty acids relocalize SNAP23 from the plasma membrane (and the translocation of GLUT 4) to the interior of the cell giving rise to insulin resistance.