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Gene Information
Gene symbol: SNCA
Gene name: synuclein, alpha (non A4 component of amyloid precursor)
HGNC ID: 11138
Synonyms: NACP, PD1, alpha-synuclein
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
19810772
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In this study, we show that annexin A5 plays a role in interacting with and reducing the toxicity of the amyloidogenic proteins, h-IAPP and alpha-synuclein.
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2 |
19810772
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Experiments with transgenic expression of alpha-synuclein in Caenorhabditis elegans show that annexin A5 reduces alpha-synuclein inclusions in vivo.
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3 |
19810772
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Using thioflavin T fluorescence, electron microscopy, and electron paramagnetic resonance, we provide evidence that substoichiometric amounts of annexin A5 inhibit h-IAPP and alpha-synuclein misfolding and fibril formation.
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