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Gene Information
Gene symbol: SORBS1
Gene name: sorbin and SH3 domain containing 1
HGNC ID: 14565
Synonyms: FLJ12406, CAP, sh3p12, ponsin, KIAA1296
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CBL | 1 hits |
| 2 | INS | 1 hits |
| 3 | INSR | 1 hits |
| 4 | PPARG | 1 hits |
| 5 | THBS1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9843961 | c-Cbl-associated protein (CAP) is a signaling protein that interacts with both c-Cbl and the insulin receptor that may be involved in the specific insulin-stimulated tyrosine phosphorylation of c-Cbl. |
| 2 | 9843961 | The stimulation of CAP expression by PPARgamma activators results from increased transcription. |
| 3 | 9843961 | This increased expression of CAP was accompanied by a potentiation of insulin-stimulated c-Cbl tyrosine phosphorylation. |
| 4 | 19689798 | Transcription factors PPARgamma, NFAT5, CREB5 and EBF1, the adipokine NAMPT, members of the insulin signaling cascade SORBS1 and IGF1 and IL6ST were repressed, while the adipokine THBS1 and GLUT4 involved in insulin signaling were induced. |