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Gene Information

Gene symbol: SOX9

Gene name: SRY (sex determining region Y)-box 9

HGNC ID: 11204

Synonyms: SRA1

Related Genes

# Gene Symbol Number of hits
1 CPA1 1 hits
2 FOXA2 1 hits
3 HNF1B 1 hits
4 INS 1 hits
5 ONECUT1 1 hits
6 PDX1 1 hits
7 PTF1A 1 hits

Related Sentences

# PMID Sentence
1 21855631 Almost all cells in PDX1(+) clusters co-express FOXA2, HNF1ß, HNF6 and SOX9 proteins, and many cells also express CPA1, NKX6.1 and PTF1a.
2 21829703 Based on in vitro studies it has been suggested that Sox9 controls expression of a network of important developmental regulators, including Tcf2/MODY5, Hnf6, and Foxa2, in pancreatic progenitor cells.
3 21829703 Employing two genetic models of temporally-controlled Sox9 inactivation in pancreatic progenitor cells, we demonstrate that contrary to in vitro findings, Sox9 is not required for Tcf2, Hnf6, or Foxa2 expression in vivo.
4 21829703 Endocrine islets from mice with reduced Sox9 gene dosage exhibited normal glucose stimulated insulin secretion.
5 21829703 Our findings show Sox9 plays an important role in endocrine development by maintaining Ngn3 and Pdx1 expression.