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Gene Information

Gene symbol: SP7

Gene name: Sp7 transcription factor

HGNC ID: 17321

Synonyms: osterix, OSX

Related Genes

# Gene Symbol Number of hits
1 ALPI 1 hits
2 ALPP 1 hits
3 MSX2 1 hits
4 RUNX2 1 hits
5 TNF 1 hits

Related Sentences

# PMID Sentence
1 12925529 The osteoblast factor osterix (Osx) is up-regulated 10-fold by Msx2, but Runx2 mRNA is unchanged; the early osteoblast marker alkaline phosphatase increases 50-fold with mineralized nodule formation enhanced 30-fold.
2 20004646 TNF-alpha increased the expression of osteogenic marker genes including RUNX2, osterix, alkaline phosphatase (ALP), and bone sialoprotein, and it also promoted matrix mineralization in VSMCs.
3 21567076 The decreased expression of ALP, osteoclacin and collagen mRNA was associated with a decrease in the expression of runt-related transcription factor 2 (Runx2), Osterix and distal-less homeobox 5 (Dlx5) and an unaltered expression of bone morphogenic protein-2 (BMP2).