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Gene Information
Gene symbol: SPTLC1
Gene name: serine palmitoyltransferase, long chain base subunit 1
HGNC ID: 11277
Synonyms: LCB1, SPTI, HSAN1, hLCB1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | SPTLC2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20522596 | Our results demonstrate that the intramyocellular accumulation of ceramide correlates strongly with the development of insulin resistance, and suggests that inhibition of SPT1 is a potentially promising target for the treatment of insulin resistance. |
| 2 | 21167294 | Lipopolysaccharide (LPS) treatment upregulated Sptlc2, a subunit of serine palmitoyltransferase (SPT), mRNA and protein in Raw264.7 and mouse peritoneal macrophages, but Sptlc1, another subunit of SPT, was not altered. |