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Gene Information
Gene symbol: SSTR2
Gene name: somatostatin receptor 2
HGNC ID: 11331
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | SST | 1 hits |
| 2 | SSTR1 | 1 hits |
| 3 | SSTR4 | 1 hits |
| 4 | SSTR5 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7587642 | In rat GH3 pituitary tumour cells exposed to 1 microM somatostatin for up to 48 h, sstr1, 3, 4 and 5 mRNA increased dramatically while sstr2 mRNA exhibited a biphasic response. |
| 2 | 15986128 | SSTR1, 2 and 4 were correlated with ER levels whereas SSTR2 showed an additional correlation with PR levels. |
| 3 | 15961235 | AD cortex showed a marked reduction in neuronal expression of SSTR4 and 5 and a modest decrease in SSTR2-like immunoreactivity without any changes in SSTR1 immunoreactive neurons. |
| 4 | 16018813 | Combined treatment caused suppression of SSTR1 below control levels but had no significant effect on SSTR2. |
| 5 | 19754922 | In contrast, agonists with high selectivity for SSTR2 or SSTR5 inhibited gall bladder emptying by approximately 50-60%, whereas SSTR1-, SSTR3- and SSTR4-selective agonists failed to influence gall bladder contraction. |
| 6 | 19754922 | In SSTR2(-/-) mice, octreotide and an SSTR5-selective agonist inhibited gall bladder emptying by approximately 50%, whereas SSTR2-selective agonists were inactive. |