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Gene Information
Gene symbol: SUMO1
Gene name: SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
HGNC ID: 12502
Synonyms: PIC1, GMP1, SMT3C, SUMO-1, SMT3H3, OFC10
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | SYT7 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21266332 | Granule localization was imaged by total internal reflection fluorescence and electron microscopy; immunoprecipitation and Western blotting were used to examine the soluble NSF attachment receptor (SNARE) complex formation and SUMO1 interaction with synaptotagmin VII. |
| 2 | 21266332 | SUMO1 impairs glucose-stimulated insulin secretion by blunting the ?-cell exocytotic response to Ca(2+). |
| 3 | 21266332 | SUMO1 coimmunoprecipitates with the Ca(2+) sensor synaptotagmin VII, and this is transiently lost upon glucose stimulation. |
| 4 | 21266332 | SENP1 overexpression also disrupts the association of SUMO1 with synaptotagmin VII and mimics the effect of glucose to enhance exocytosis. |