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Gene Information
Gene symbol: SUV420H2
Gene name: suppressor of variegation 4-20 homolog 2 (Drosophila)
HGNC ID: 28405
Synonyms: MGC2705, KMT5C
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
21357467
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Hyperglycemia (diabetes or galactosemia) increased H4K20me3, acetyl H3K9, and NF-?B p65 at the promoter and enhancer of retinal sod2, upregulated protein and gene expression of SUV420h2, and increased the interactions of acetyl H3K9 and NF-?B p65 to H4K20me3.
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2 |
21357467
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Reversal of hyperglycemia failed to prevent increases in H4K20me3, acetyl H3K9, and NF-?B p65 at sod2, and sod2 and SUV420h2 continued to be abnormal.
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3 |
21357467
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Silencing SUV420h2 by its small interfering RNA in retinal endothelial cells prevented a glucose-induced increase in H4K20me3 at the sod2 enhancer and a decrease in sod2 transcripts.
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