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Gene Information
Gene symbol: TBX21
Gene name: T-box 21
HGNC ID: 11599
Synonyms: TBLYM, T-bet
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GATA3 | 1 hits |
| 2 | HSPD1 | 1 hits |
| 3 | IFNG | 1 hits |
| 4 | IL10 | 1 hits |
| 5 | IL12A | 1 hits |
| 6 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15749853 | We now report that HSP60 in vitro differentially modulates the expression of Th1/Th2 transcription factors in human T cells: HSP60 down-regulates T-bet, NF-kappaB, and NFATp and up-regulates GATA-3, leading to decreased secretion of TNF-alpha and IFN-gamma and enhanced secretion of IL-10. |
| 2 | 16888219 | In the pancreas of VIP-treated animals, regulatory T cell markers predominate, as indicated by the upregulation of FoxP3 and transforming growth factor-beta (TGF-beta), and the downregulation of the transcription factor, T-bet. |
| 3 | 21368230 | Naive Tregs were capable of upregulating expression of Th1-associated T-bet, CXCR3, and IFN-? in response to IL-12. |