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Gene Information
Gene symbol: TCF3
Gene name: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
HGNC ID: 11633
Synonyms: E2A, ITF1, MGC129647, MGC129648, bHLHb21, VDIR, E47
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | PLAU | 1 hits |
| 3 | SST | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7912577 | We compared the neuropeptide somatostatin promoter, which binds CREB and is activated by cAMP, to the adenovirus E2A promoter, which binds ATF but is not activated by cAMP, to determine which specific nucleotides within a CREB/ATF recognition sequence confer cAMP responsiveness. |
| 2 | 12586550 | HD transgenic mice develop an age-dependent reduction of insulin mRNA expression and diminished expression of key regulators of insulin gene transcription, including the pancreatic homeoprotein PDX-1, E2A proteins, and the coactivators CBP and p300. |
| 3 | 16099819 | The coactivator Bridge-1 (PSMD9) regulates the transcriptional activation of glucose-responsive enhancers in the insulin gene in a dose-dependent manner via PDZ domain-mediated interactions with E2A transcription factors. |