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Gene Information

Gene symbol: TEK

Gene name: TEK tyrosine kinase, endothelial

HGNC ID: 11724

Synonyms: TIE2, TIE-2, VMCM1, CD202b

Related Genes

# Gene Symbol Number of hits
1 ANGPT1 1 hits
2 ANGPT2 1 hits
3 ANPEP 1 hits
4 ST3GAL4 1 hits
5 TM7SF2 1 hits

Related Sentences

# PMID Sentence
1 18436850 CD13 (aminopeptidase N) expression in pericytes was determined by Western blot analysis and Ang effects verified with Tie-2 antisense treatment.
2 20832563 Angiopoientin-1 (Ang1) is a specific growth factor that induces vascularization via the Tie2 or Tie1 receptor.
3 21113176 Ang-1 (250 ng/mL) increased Tie-2 activation, inhibited cell apoptosis, and promoted angiogenesis.
4 21113176 Ang-1 activates the Tie-2 pathway and restores hyperglycemia-induced myocardial microvascular endothelial dysfunction.
5 18408125 Angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) are the two ligands of the Tie-2 receptor, a receptor tyrosine kinase that is expressed on the endothelium.
6 18408125 In STZ mice, Ang-2 expression was elevated, whereas Tie-2 expression was reduced, and neither was significantly altered by ischemia.