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Gene Information
Gene symbol: TFAP4
Gene name: transcription factor AP-4 (activating enhancer binding protein 4)
HGNC ID: 11745
Synonyms: AP-4, bHLHc41
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12672257 | Ip(5)I and Ip(6)I antagonized Ap(5)A-mediated inhibition of insulin release. [(3)H]Thymidine incorporation into VSMC was not influenced by either synthetic diadenosine polyphosphate analogue, indicating that Ap(4)A does not act by itself in this case but (active) degradation products mediate the effect. |
| 2 | 12672257 | The data indicate the following. (1) Since nondegradable compounds inhibit insulin release as well as Ap(4)A, it is Ap(4)A itself and not any of its degradation products that induces this effect. (2) Diadenosine polyphosphate effects on cell proliferation are mediated via a degradation product in contrast to their effect on insulin release. (3) Ip(5)I and Ip(6)I act like antagonists. |