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Gene Information

Gene symbol: TJP1

Gene name: tight junction protein 1

HGNC ID: 11827

Synonyms: ZO-1, MGC133289, DKFZp686M05161

Related Genes

# Gene Symbol Number of hits
1 CLDN5 1 hits
2 CNR1 1 hits
3 SERPINF1 1 hits
4 SYNPO 1 hits

Related Sentences

# PMID Sentence
1 20627932 Diabetes also decreased occludin and claudin-5 levels and altered the distribution of ZO-1 and occludin in retinal vessels.
2 20470857 Together, our results indicate that PEDF could possibly act as potent anti-permeability molecule by targeting the PI3K/Akt signaling pathway by suppressing if NADPH oxidase mediated ROS generation and ZO-1 tight junction protein and it offers potential targets to inhibit the ocular related diseases such as diabetic retinopathy.
3 20068137 Expression of nephrin, podocin, synaptopodin, and zonula occludens-1 (ZO-1) was assessed by immunofluorescence and real-time PCR.
4 20068137 Furthermore, CB1 blockade completely prevented diabetes-induced downregulation of nephrin, podocin, and ZO-1.