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Gene Information
Gene symbol: TNFSF11
Gene name: tumor necrosis factor (ligand) superfamily, member 11
HGNC ID: 11926
Synonyms: TRANCE, RANKL, OPGL, ODF, CD254
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AHSG | 1 hits |
| 2 | BGLAP | 1 hits |
| 3 | BMP7 | 1 hits |
| 4 | GLA | 1 hits |
| 5 | SPP1 | 1 hits |
| 6 | TNFRSF11A | 1 hits |
| 7 | TNFRSF11B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18072013 | The aim of this investigation was to evaluate potential age- and gender-related changes in free RANKL and total RANKL (free RANKL+RANKL/osteoprotegerin complexes). |
| 2 | 20809534 | OPG inhibits vascular calcification in vitro and high serum levels have been demonstrated in type 2 diabetes, but serum RANKL and TRAIL and their potential correlation with well-established biomarkers of subclinical vascular inflammation such as high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6) have not been described. |
| 3 | 20716128 | Arterial calcification is the result of a complex interplay between stimulating (bone morphogenetic protein type 2 [BMP-2], RANKL) and inhibitory (matrix Gla protein, BMP-7, osteoprotegerin, fetuin-A, osteopontin) proteins. |
| 4 | 21464945 | The osteoblast-specific bone forming markers osteocalcin and osteoprotegerin were decreased in TH mice, whereas osteoclast-driven bone resorption markers such as IL-6 and RANKL were significantly elevated in the bone marrow and blood of TH mice. |
| 5 | 19624408 | Plasma concentrations of receptor activator of nuclear factor-kappaB ligand (RANKL), osteoprotegerin (OPG), C-terminal telopeptide of type 1 collagen and osteocalcin were measured in type 1 diabetes mellitus patients (n=63) and non-diabetics (n=38) who were also subdivided on the basis of their periodontal status. |
| 6 | 21659498 | The receptor activator of nuclear factor-?B (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) signaling pathway (RANKL/RANK/OPG signaling) is implicated in the osteolysis associated with diabetic Charcot neuroarthropathy (CN); however, the links with medial arterial calcification (MAC) seen in people with CN are unclear. |