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Gene Information
Gene symbol: TNKS
Gene name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
HGNC ID: 11941
Synonyms: TIN1, TINF1, TNKS1, PARP-5a, PARP5A, pART5
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | INS | 1 hits |
| 3 | LEP | 1 hits |
| 4 | SLC2A4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19651815 | Tankyrase (TNKS) is a Golgi-associated poly-ADP-ribose polymerase that is implicated in the regulation of GLUT4 trafficking in 3T3-L1 adipocytes. |
| 2 | 19651815 | TNKS-deficient mice consume increased amounts of food (by 34%) but have decreased plasma leptin levels and a >50% reduction in epididymal and perirenal fat pad size. |
| 3 | 19651815 | Although TNKS deficiency does not compromise insulin-stimulated GLUT4 translocation in primary adipocytes, it leads to the post-transcriptional upregulation of GLUT4 and adiponectin in adipocytes and increases plasma adiponectin levels. |
| 4 | 19651815 | TNKS-deficient mice exhibit increases in energy expenditure, fatty acid oxidation, and insulin-stimulated glucose utilization. |