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Gene Information

Gene symbol: TNNT2

Gene name: troponin T type 2 (cardiac)

HGNC ID: 11949

Related Genes

#	Gene Symbol	Number of hits
1	ALB	1 hits
2	GDF15	1 hits
3	HBB	1 hits
4	IDH3B	1 hits

Related Sentences

#	PMID	Sentence
1	15741207	In univariate analysis, concentrations of cTnT >/=0.035 ng/ml, increased LVMI, diabetes, serum albumin and age were all strong predictors of total mortality.
2	20855664	In a comprehensive multiple-variable Cox regression model that included clinical prognostic variables, B-type natriuretic peptide, high-sensitivity C-reactive protein, and high-sensitivity troponin T, GDF-15 remained independently associated with mortality (hazard ratio, 1.007; 95% confidence interval, 1.001 to 1.014; P=0.02) but not first morbid event.
3	20855664	Increases in GDF-15 over 12 months were independently associated with the risks of future mortality and first morbid event also after adjustment for clinical prognostic variables, B-type natriuretic peptide, high-sensitivity C-reactive protein, and high-sensitivity troponin T and their changes.
4	21354350	Among the decreased proteins, 3 are involved in heart structure (one isoform of desmin, troponin T2 and ?-cardiac actin), 3 are involved in energy metabolism (mitochondrial ATP synthase ? subunit, adenylate kinase and creatine kinase) and one is a component of the citric acid cycle (isocitrate dehydrogenase 3).
5	21632491	In models adjusted for traditional risk factors and hemoglobin A(1c), detectable high-sensitivity cardiac troponin T was associated with subsequent CVD (myocardial infarction, stroke, cardiovascular death) in diabetic women (adjusted hazard ratio, 1.79; 95% confidence interval, 1.04 to 3.07, P=0.036) but not nondiabetic women (adjusted hazard ratio, 1.13; 95% confidence interval, 0.82 to 1.55; P=0.46).