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Gene Information
Gene symbol: TPT1
Gene name: tumor protein, translationally-controlled 1
HGNC ID: 12022
Synonyms: TCTP, fortilin
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD28 | 1 hits |
| 2 | IL2 | 1 hits |
| 3 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19144262 | Since CD28 co-stimulation is essential for the survival of CD4+CD25high T cells, we determined whether CD28-upregulated translationally controlled tumor protein (TCTP) prolongs the survival of CD4+CD25high regulatory T cells (Tregs) by a transgenic approach. |
| 2 | 19144262 | The TCTP transgene prevents Tregs from undergoing apoptosis induced by interleukin-2 withdrawal-, dexamethasone-, cyclophosphamide-, and anti-Fas treatment in vitro. |
| 3 | 19144262 | Moreover, TCTP transgenic Tregs inhibit the development of autoimmune diabetes due to increased survival of suppressive Tregs and decreased expression of pancreatic TNF-alpha. |