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Gene Information
Gene symbol: TRPC1
Gene name: transient receptor potential cation channel, subfamily C, member 1
HGNC ID: 12333
Synonyms: HTRP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | F2 | 1 hits |
| 2 | STIM1 | 1 hits |
| 3 | TRPC6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17699555 | In cultured human MCs, high glucose significantly reduced expression of TRPC6 protein, but there was no effect on either TRPC1 or TRPC3. |
| 2 | 21303733 | Treatment with TG or the agonist thrombin enhanced co-immunoprecipitation of STIM1 with Orai1, hTRPC1 and hTRPC6 in platelets from healthy donors, a response that was significantly reduced in platelets from diabetic patients. |
| 3 | 21303733 | Our results indicate that store-operated divalent cation entry is reduced in platelets from type 2 diabetic subjects, which is likely mediated by impairment of the association of STIM1 with the channel subunits Orai1, hTRPC1 and hTRPC6 and might be involved in the pathogenesis of the altered platelet responsiveness observed in diabetic patients. |