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Gene Information
Gene symbol: TSC22D1
Gene name: TSC22 domain family, member 1
HGNC ID: 16826
Synonyms: TSC22, MGC17597
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
17622752
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It interacts with the TSC-22 gene involved in the TGF-beta signaling pathway, promoting the development of diabetic nephropathy.
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2 |
20713358
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TGF-? also enhanced protein levels of Tsc-22 (TGF-?-stimulated clone 22) and collagen type I ?-2 (Col1a2) expression in MC through far upstream enhancer E-boxes by interaction of Tsc-22 with an E-box regulator, Tfe3.
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3 |
20713358
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Co-immunoprecipitation assays revealed that TGF-? promoted the interaction of Tsc-22 with Tfe3.
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4 |
20713358
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These results demonstrate that post-transcriptional regulation of Tsc-22 mediated through Ybx1, a miR-216a target, plays a key role in TGF-?-induced Col1a2 in MC related to the pathogenesis of diabetic nephropathy.
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