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Gene Information
Gene symbol: UGCG
Gene name: UDP-glucose ceramide glucosyltransferase
HGNC ID: 12524
Synonyms: GCS
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | INS | 1 hits |
| 2 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11707432 | Pharmacological depletion of GM3 in adipocytes by an inhibitor of glucosylceramide synthase prevented the TNF-alpha-induced defect in insulin-dependent tyrosine phosphorylation of IRS-1 and also counteracted the TNF-alpha-induced serine phosphorylation of IRS-1. |
| 2 | 19731235 | We have shown that the iminosugar N-(5'-adamantane-1'-yl-methoxy)-pentyl-1-deoxynojirimycin (AMP-DNM), an inhibitor of the enzyme glucosylceramide synthase, is a potent enhancer of insulin signaling in rodent models for insulin resistance and type 2 diabetes. |