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Gene Information
Gene symbol: UNC13B
Gene name: unc-13 homolog B (C. elegans)
HGNC ID: 12566
Synonyms: hmunc13, Unc13h2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | RAPGEF3 | 1 hits |
| 2 | UNC13A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17639022 | To determine specific contributions within Epac-Rim2-Munc13-1 interaction sites accounting for cAMP rescue of exocytosis caused by Munc13-1 deficiency, we found that blockade of Rim2-Munc13-1 interaction with Rim-Munc13-1-binding domain peptide abolished cAMP rescue, whereas blockade of Epac-Rim2 interaction with Rim2-PDZ peptide only moderately reduced refilling with little effect on RRP. cAMP rescue of priming defects caused by Munc13-1 deficiency via Epac and PKA signaling pathways requires downstream Munc13-1-Rim2 interaction. |