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Gene Information
Gene symbol: WNT4
Gene name: wingless-type MMTV integration site family, member 4
HGNC ID: 12783
Synonyms: WNT-4
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | CASP3 | 1 hits |
| 3 | GSK3B | 1 hits |
| 4 | INS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21827825 | Blastocysts grown in diabetic rabbits are retarded in development, a finding which supports our current results that insulin is highly likely required for early mesoderm formation in rabbit blastocysts by inducing a distinct spatiotemporal expression profile of Wnt3a, Wnt4 and Brachyury. |
| 2 | 16943306 | High glucose downregulated Wnt4 and Wnt5a expression and the subsequent nuclear translocation of beta-catenin, whereas it increased glycogen synthase kinase-3beta (GSK-3beta) and caspase-3 activities and apoptosis of glomerular mesangial cells. |
| 3 | 16943306 | Suppression of GSK-3beta activation or increase in nuclear beta-catenin by transfection of Wnt4 or Wnt5a or stable beta-catenin (S33Y) reversed Akt activation and reduced the high glucose-mediated caspase-3 cleavage and cell apoptosis. |