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Gene Information
Gene symbol: ADIPOQ
Gene name: adiponectin, C1Q and collagen domain containing
HGNC ID: 13633
Synonyms: ACRP30, AdipoQ, apM1, GBP28, adiponectin
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18431507
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Adiponectin deficiency in mice induced oxidative stress, fusion of podocyte foot processes in the kidney glomerulus, and urinary albumin excretion.
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2 |
18431508
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In cultured podocytes, adiponectin administration was associated with increased activity of AMPK, and both adiponectin and AMPK activation reduced podocyte permeability to albumin and podocyte dysfunction, as evidenced by zona occludens-1 translocation to the membrane.
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3 |
18431508
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Ad(-/-) mice treated with adiponectin exhibited normalization of albuminuria, improvement of podocyte foot process effacement, increased glomerular AMPK activation, and reduced urinary and glomerular markers of oxidant stress.
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4 |
18941912
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ADIPOR1 and catalytic AMPK sub-units alpha1 and alpha2 were revealed in normal rat glomeruli and incubation of freshly isolated rat glomeruli with either adiponectin or AICAR led to the activation by phosphorylation of catalytic AMPK.
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5 |
18941912
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It is concluded that glomerular cells express a functional adiponectin receptor ADIPOR1 which, through activation of AMPK, may play important roles in the control of oxidative stress and cell survival within the glomerulus.
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6 |
21694920
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Adiponectin potentiates insulin in its post-receptor signaling resulting in glucose oxidation in mitochondria.
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