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Gene Information
Gene symbol: ANG
Gene name: angiogenin, ribonuclease, RNase A family, 5
HGNC ID: 483
Synonyms: RNASE5
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACE2 | 1 hits |
| 2 | AGT | 1 hits |
| 3 | BECN1 | 1 hits |
| 4 | MAPK1 | 1 hits |
| 5 | NPHS1 | 1 hits |
| 6 | REN | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17429035 | These findings demonstrate that POD express a functional intrinsic renin-angiotensin system characterized by neprilysin, aminopeptidase A, ACE2, and renin activities, which predominantly lead to ANG-(1-7) and ANG-(1-9) formation, as well as ANG II degradation. |
| 2 | 20007350 | Recent work suggests renin inhibition improves proteinuria comparable to ANG type 1 receptor (AT1R) blockade (ARB). |
| 3 | 18204248 | The present study evaluates the effects of Ang II infusion in rats on podocyte nephrin expression and apoptosis and the molecular mechanisms involved in Ang II-induced proteinuria and mesangial expansion. |
| 4 | 18204248 | On day 14, the Ang II-infused rats showed narrowing of the slit diaphragm, an increase in podocyte nephrin mRNA and protein expression, and alterations in its distribution along the foot processes. |
| 5 | 18204248 | These results suggest that changes in nephrin expression may play a role in the pathogenesis of Ang II-induced podocyte apoptosis. |
| 6 | 20484657 | ANG II also enhanced podocyte expression of autophagic genes such as LC3-2 and beclin-1. |
| 7 | 20075844 | Recently, prorenin bound to (pro)renin receptor ((P)RR) was found and shown to evoke two pathways; the generation of Ang peptides and the receptor-dependent activation of extracellular signal-related protein kinase (ERK). |