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Gene Information

Gene symbol: ARNT

Gene name: aryl hydrocarbon receptor nuclear translocator

HGNC ID: 700

Synonyms: HIF-1beta, bHLHe2

Related Genes

# Gene Symbol Number of hits
1 EPAS1 1 hits
2 HIF1A 1 hits
3 VEGFA 1 hits

Related Sentences

# PMID Sentence
1 12660327 In response to hypoxia, stabilized HIF-1alpha and HIF-2alpha proteins bind HIF-1beta and initiate expression of genes that alleviate hypoxic stress, including those promoting neovascularization.
2 12660327 Because VEGF is highly expressed by metanephric podocytes and collecting ducts, developing mouse kidney was examined for the presence and distribution of HIF-1alpha, HIF-2alpha, and HIF-1beta.
3 12660327 Both HIF-1 and HIF-2 heterodimers were identified in newborn kidney lysates by immunoprecipitation with HIF-1alpha, HIF-2alpha, and HIF-1beta antibodies and Western blots.
4 12660327 Immunohistochemistry of newborn kidney demonstrated widespread expression of HIF-1beta protein in nuclei of glomeruli and all tubular segments, whereas HIF-2alpha protein expression was more restricted and localized chiefly to podocytes of developing glomeruli and developing tubules.