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Gene Information
Gene symbol: ARNT
Gene name: aryl hydrocarbon receptor nuclear translocator
HGNC ID: 700
Synonyms: HIF-1beta, bHLHe2
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
12660327
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In response to hypoxia, stabilized HIF-1alpha and HIF-2alpha proteins bind HIF-1beta and initiate expression of genes that alleviate hypoxic stress, including those promoting neovascularization.
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2 |
12660327
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Because VEGF is highly expressed by metanephric podocytes and collecting ducts, developing mouse kidney was examined for the presence and distribution of HIF-1alpha, HIF-2alpha, and HIF-1beta.
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3 |
12660327
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Both HIF-1 and HIF-2 heterodimers were identified in newborn kidney lysates by immunoprecipitation with HIF-1alpha, HIF-2alpha, and HIF-1beta antibodies and Western blots.
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4 |
12660327
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Immunohistochemistry of newborn kidney demonstrated widespread expression of HIF-1beta protein in nuclei of glomeruli and all tubular segments, whereas HIF-2alpha protein expression was more restricted and localized chiefly to podocytes of developing glomeruli and developing tubules.
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