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Gene Information
Gene symbol: BMP7
Gene name: bone morphogenetic protein 7
HGNC ID: 1074
Synonyms: OP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NPHS1 | 1 hits |
| 2 | SMAD1 | 1 hits |
| 3 | SMAD5 | 1 hits |
| 4 | TGFB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17804487 | In these cells, BMP7 effectively activates smad5 (but not smad1) and raises p38 phosphorylation [which is also increased by transforming growth factor-beta (TGF-beta)]. |
| 2 | 17804487 | HG as well as TGF-beta raise caspase-3 activity, increase apoptosis, and reduce cell survival which is, in part, blocked by BMP7. |
| 3 | 17804487 | Knockdown and forced expression studies indicate that smad5 is required as well as sufficient for these actions of BMP7. |
| 4 | 19403392 | To evaluate the effect of bone morphogenic protein 7 (BMP-7) on nephrin expression and distribution in diabetic rat kidneys. |
| 5 | 19403392 | The rats in BMP-7 group showed less urinary protein excretion, lower TGF-beta1 expression and greater glomerular podocyte number than those in the DM group, and the expression and distribution of nephrin remained normal in the kidney. |
| 6 | 19403392 | Administration of BMP-7 can significantly suppress the down-regulation of nephrin expression and maintain its normal distribution in the podocytes in diabetic rats possibly in association with a direct suppression of TGF-betasignaling. |