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Gene Information

Gene symbol: CASP8

Gene name: caspase 8, apoptosis-related cysteine peptidase

HGNC ID: 1509

Synonyms: MCH5, MACH, FLICE, Casp-8

Related Genes

# Gene Symbol Number of hits
1 CASP9 1 hits
2 FAS 1 hits

Related Sentences

# PMID Sentence
1 16421179 Apoptosis induced by each TM was associated with a significant (approximately 400%) increase in caspase 8 activity, but no change in caspase 9 activity, and Western analyses revealed a marked up-regulation of Fas (approximately 500%) and FADD (approximately 300%) with no change in expression of Bax, Bcl-2, or Bcl-xL.
2 15975999 In cultured podocytes, cross-linking of the Fas receptor to mimic ligand binding induced caspase 8 activity and apoptosis in both normal and HIVAN podocytes.