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Gene Information
Gene symbol: CASP8
Gene name: caspase 8, apoptosis-related cysteine peptidase
HGNC ID: 1509
Synonyms: MCH5, MACH, FLICE, Casp-8
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
16421179
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Apoptosis induced by each TM was associated with a significant (approximately 400%) increase in caspase 8 activity, but no change in caspase 9 activity, and Western analyses revealed a marked up-regulation of Fas (approximately 500%) and FADD (approximately 300%) with no change in expression of Bax, Bcl-2, or Bcl-xL.
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2 |
15975999
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In cultured podocytes, cross-linking of the Fas receptor to mimic ligand binding induced caspase 8 activity and apoptosis in both normal and HIVAN podocytes.
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