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Gene Information
Gene symbol: CD80
Gene name: CD80 molecule
HGNC ID: 1700
Synonyms: B7.1, B7-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL13 | 1 hits |
| 2 | TGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19556042 | Recent studies suggest that interleukin 13, a known stimulator of IgE response, may mediate proteinuria in patients with minimal change disease because of its ability to directly induce CD80 expression on the podocyte. |
| 2 | 21052729 | We further hypothesize that under normal circumstances, CD80 expression is only transiently expressed and proteinuria is minimal due to rapid autoregulatory response by circulating T regulatory cells or by the podocyte itself, probably due to the expression of factors [cytotoxic T-lymphocyte-associated (CTLA)-4, interleukin (IL)-10, and possibly transforming growth factor (TGF)-?] that downregulate the podocyte CD80 response. |
| 3 | 21839364 | Interleukin-13 or microbial products via Toll-like receptors could be factors that induce CD80 expression on podocytes. |