|
Gene Information
Gene symbol: CDC42
Gene name: cell division cycle 42 (GTP binding protein, 25kDa)
HGNC ID: 1736
Synonyms: G25K, CDC42Hs
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
17569780
|
Here we show that synaptopodin directly binds to IRSp53 and suppresses Cdc42:IRSp53:Mena-initiated filopodia formation by blocking the binding of Cdc42 and Mena to IRSp53.
|
2 |
17569780
|
The identification of synaptopodin as an inhibitor of Cdc42:IRSp53:Mena signaling defines a novel antiproteinuric signaling pathway and offers new targets for the development of antiproteinuric therapeutic modalities.
|
3 |
18084301
|
Mechanistically, uPAR is required to activate alphavbeta3 integrin in podocytes, promoting cell motility and activation of the small GTPases Cdc42 and Rac1.
|
4 |
21734098
|
Analysis of RhoA family GTPase activity demonstrated that treatment with AGE-BSA or NRP1 depletion inhibited as well the activation of the Rac-1 and Cdc42 but did not affect RhoA activity.
|
|