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Gene Information

Gene symbol: CDC42

Gene name: cell division cycle 42 (GTP binding protein, 25kDa)

HGNC ID: 1736

Synonyms: G25K, CDC42Hs

Related Genes

# Gene Symbol Number of hits
1 BAIAP2 1 hits
2 ENAH 1 hits
3 NRP1 1 hits
4 PLAUR 1 hits
5 SYNPO 1 hits

Related Sentences

# PMID Sentence
1 17569780 Here we show that synaptopodin directly binds to IRSp53 and suppresses Cdc42:IRSp53:Mena-initiated filopodia formation by blocking the binding of Cdc42 and Mena to IRSp53.
2 17569780 The identification of synaptopodin as an inhibitor of Cdc42:IRSp53:Mena signaling defines a novel antiproteinuric signaling pathway and offers new targets for the development of antiproteinuric therapeutic modalities.
3 18084301 Mechanistically, uPAR is required to activate alphavbeta3 integrin in podocytes, promoting cell motility and activation of the small GTPases Cdc42 and Rac1.
4 21734098 Analysis of RhoA family GTPase activity demonstrated that treatment with AGE-BSA or NRP1 depletion inhibited as well the activation of the Rac-1 and Cdc42 but did not affect RhoA activity.