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Gene Information

Gene symbol: CLU

Gene name: clusterin

HGNC ID: 2095

Synonyms: SGP-2, SP-40, TRPM-2, KUB1, CLU1, CLU2

Related Genes

# Gene Symbol Number of hits
1 AGT 1 hits
2 LDLR 1 hits
3 LRP2 1 hits

Related Sentences

# PMID Sentence
1 16775601 Clusterin has been reported as a megalin ligand in immunodeposits, although its role has not been clarified.
2 16775601 In vitro experiments were performed to investigate the role of clusterin during podocyte damage by MGN serum and define clusterin binding to human podocytes, where megalin is known to be absent.
3 16775601 Clusterin, C5b-9, and pPKC-alpha/beta showed highly variable glomerular staining, where high clusterin profiles were inversely correlated to C5b-9 and PKC-alpha/beta expression (P=0.029), and co-localized with the low-density lipoprotein receptor (LDL-R).
4 16775601 Preliminary in vitro experiments showed podocyte binding of biotinilated clusterin, co-localization with LDL-R and specific binding inhibition with anti-LDL-R antibodies and with specific ligands.
5 18949565 We also aimed to investigate the post-effects of angiotensin II blockage treatment on clusterin expression and to compare these with apoptosis.