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Gene Information
Gene symbol: DUSP1
Gene name: dual specificity phosphatase 1
HGNC ID: 3064
Synonyms: HVH1, CL100, MKP-1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18625721
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Here we show that atRA, through cAMP and PKA, triggers a feed-forward loop involving CREB and USF1 to induce biphasic stimulation of MKP1. atRA stimulated CREB and USF1 binding to the MKP1 gene promoter, as shown by gel shifting and chromatin immunoprecipitation assays.
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2 |
18625721
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CREB directly mediated the early phase of atRA-induced MKP1 stimulation; whereas the later phase was mediated by CREB indirectly through induction of USF1.
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