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Gene Information

Gene symbol: EPAS1

Gene name: endothelial PAS domain protein 1

HGNC ID: 3374

Synonyms: MOP2, PASD2, HIF2A, HLF, bHLHe73

Related Genes

# Gene Symbol Number of hits
1 ARNT 1 hits
2 ENG 1 hits
3 HIF1A 1 hits
4 VEGFA 1 hits

Related Sentences

# PMID Sentence
1 12660327 Because VEGF is highly expressed by metanephric podocytes and collecting ducts, developing mouse kidney was examined for the presence and distribution of HIF-1alpha, HIF-2alpha, and HIF-1beta.
2 12660327 Both HIF-1 and HIF-2 heterodimers were identified in newborn kidney lysates by immunoprecipitation with HIF-1alpha, HIF-2alpha, and HIF-1beta antibodies and Western blots.
3 12660327 Immunohistochemistry of newborn kidney demonstrated widespread expression of HIF-1beta protein in nuclei of glomeruli and all tubular segments, whereas HIF-2alpha protein expression was more restricted and localized chiefly to podocytes of developing glomeruli and developing tubules.
4 16374431 HIF-2alpha colocalized with the endothelium-associated angiogenic factor, endoglin.