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Gene Information
Gene symbol: FADD
Gene name: Fas (TNFRSF6)-associated via death domain
HGNC ID: 3573
Synonyms: MORT1, GIG3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ALB | 1 hits |
| 2 | BAX | 1 hits |
| 3 | BCL2 | 1 hits |
| 4 | BCL2L1 | 1 hits |
| 5 | CASP3 | 1 hits |
| 6 | CASP9 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16421179 | Apoptosis induced by each TM was associated with a significant (approximately 400%) increase in caspase 8 activity, but no change in caspase 9 activity, and Western analyses revealed a marked up-regulation of Fas (approximately 500%) and FADD (approximately 300%) with no change in expression of Bax, Bcl-2, or Bcl-xL. |
| 2 | 20827429 | Compared with control group, proteinuria, FPW, apoptotic podocytes, caspase-3 activity, the protein expressions of p-Smad2/3, Fas, FADD, and Bax were significantly increased, podocyte density, p-Smad1/5/8 and Bcl-2 expression were decreased in ADR group. 1,25(OH)(2)D(3) significantly reduced proteinuria, FPW, caspase-3 activity, expressions of p-Smad2/3, Fas, FADD, and Bax and apoptosis of podocytes, but increased serum albumin, number of viable podocytes , p-Smad1/5/8 and Bcl-2 expression in ADR treated rats. |
| 3 | 20827429 | ADR-induced podocyte apoptosis was associated with the imbalance of p-Smad2/3, p-Smad1/5/8 the activity of caspase-3 and aberrant expressions of, Fas, FADD, Bax and Bcl-2. |