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Gene Information
Gene symbol: HGF
Gene name: hepatocyte growth factor (hepapoietin A; scatter factor)
HGNC ID: 4893
Synonyms: SF, F-TCF, HGFB, HPTA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | MAPK1 | 1 hits |
| 2 | MET | 1 hits |
| 3 | NPHS1 | 1 hits |
| 4 | WT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20375988 | When HGF was expressed ectopically in vivo, it ameliorated adriamycin-induced albuminuria, preserved WT1 and nephrin expression, and inhibited podocyte apoptosis. |
| 2 | 20375988 | In vitro, HGF was able to preserve WT1 and nephrin expression in cultured podocytes after adriamycin treatment. |
| 3 | 21514418 | In vitro, HGF stimulation of podocytes resulted in antiapoptotic phosphorylation of AKT and extracellular signal-regulated kinase (ERK) and induction of X-linked inhibitor of apoptosis protein (XIAP). |
| 4 | 21514418 | Decreased antiapoptotic Met signaling in podocytes, probably due to decreased HGF secretion by glomerular epithelial cells, could contribute to podocyte loss and FSGS in TxG. |
| 5 | 21775482 | Exogenous expression of HGF produced evidently beneficial effects, leading to restoration of Wilms' tumor-1 (WT1) and ?-actinin-4 expression and attenuation of ultrastructural damage of the podocytes. |
| 6 | 21775482 | In vitro, HGF not only restored WT1 and ?-actinin-4 expression but also inhibited albumin leakage of podocytes incubated with PAN in a Transwell culture chamber. |